On the outskirts of the city of Bombay, near the train terminus Titwala, is a small village called Vasundhari, situated on the banks of the river Kalu. About 15,000 men, women and children live here. The entire village is dying slowly of an undiagnosed disease that no known medicine can cure. They are dying of what one could at best describe as the Vasundhari Syndrome. Talkie includes a local milkman, police patil of the village, Ex- sarpanch, an anganwadi teacher besides the ecologist Dr. Rashmi Mayur.